Towards personalized medicine in Parkinson's disease

The project led by Christine Brefel-Courbon aims to study the impact of personality as a key component of personalized medicine, on the symptomatology and management of patients with Parkinson's disease, using clinical, psychological, genetic and neuroimaging approaches. 

The research results aim to allow a better orientation of patients towards a second-line treatment adapted to their singularities thanks to the consideration of their personality.  They  should also make it possible to adapt drug prescriptions as best as possible according to the personality of patients to limit the occurrence of foreseeable adverse effects. Finally, personality could also allow a better identification of Parkinson's patients at risk of developing chronic pain to treat them earlier. In the long term, this project aims to improve the personalized care of Parkinson's patients by offering them the best treatment to manage their symptoms while limiting the risk of adverse effects.