Food & Nutrition
Mental Health & Neurology
Mécénat des Mutuelles
ODYCÉ: Perinatal Exposure to Omega 3 and 6 During the "First 1,000 days" and Dys Disorders in Children
The first 1,000 days of life represent a critical period for brain development, during which perinatal exposure to polyunsaturated fatty acids (PUFAs) may influence child’s neurodevelopment. While associations between PUFAs and IQ, autism spectrum disorder, or attention-deficit/hyperactivity disorder have already been documented, their links with specific learning disorders ("dys" disorders) — which affect 7% of children and have major consequences — remain unexplored. Few epidemiological studies have addressed this issue, despite the lasting impact of these disorders on academic performance and quality of life.
The ODYCÉ project, led by Barbara Heude, Jonathan Bernard and Martine Armand, aims to identify early—particularly nutritional—factors influencing the development of specific learning disorders (DYS) in children. This epidemiological project is based on an observational approach in the general population, leveraging data and biological samples from child cohorts followed since birth.
Specifically, it seeks to investigate the associations between polyunsaturated fatty acid exposure profiles during the periconceptional period and cognitive development trajectories, including the emergence of DYS disorders.
The ODYCÉ project will enhance our understanding of the links between perinatal nutrition and the onset of these disorders, while identifying actionable levers for more targeted prevention and management.
Ultimately, this work could open innovative avenues for preventing learning disorders in children. Collectively, these efforts will contribute to promoting overall health and well-being through optimal nutrition during the first 1,000 days of life.
Barbara
HEUDE
Institution
INSERM
Country
Nationality
French
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