Host factors for influenza A virus entry as novel drug targets

Despite the use of seasonal vaccines against influenza A virus (IAV), the threat of pandemic remains real and resistance to existing drugs is increasing. This is partly because they act on proteins of the virus itself. Pohl’s approach is to target, instead, the human factors necessary for the virus to enter our cells. Her work focuses on identifying and trying to block these partners of IAV. As many viruses use similar infection routes, such treatments could be effective on other viruses, too.

Sidestepping flu resistance to existing drugs

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Marie
POHL

Institution

University of Zurich

Country

Switzerland

Nationality

German

Health

Pandemics & Infectious Diseases

Prevention & Personalised Health

Bacteria & Other Microorganisms

Children & Youth

Genetics & Omics

Immune System

Mécénat des Mutuelle

France

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