Medical Treatment & Drug Development
Mécénat des Mutuelles
France
Accelerating drug innovation with the Euridis school and its DDD Challenge
The discovery and development of new medicines is a long, complex, and highly regulated process. Yet, many severe pathologies still lack effective treatments: aggressive cancers such as glioblastoma or metastatic breast tumors, autoimmune diseases such as lupus, neurodegenerative and demyelinating disorders, as well as chronic pain and inflammatory syndromes that are often only managed symptomatically.
France has considerable assets and internationally recognized expertise at every stage of the therapeutic innovation cycle, from fundamental research to clinical evaluation. However, the national drug development ecosystem remains fragmented at the academic level and is insufficiently connected to the network of biotechnology companies. These companies have proven to be critical drivers of breakthrough therapeutic strategies, particularly in addressing new medical challenges.
Strengthening integration between academic, clinical, and industrial stakeholders is therefore essential to accelerate the availability of innovative solutions, shorten development timelines, and respond to major unmet medical needs.
The project addresses a dual challenge: on one hand, the increasing complexity of drug development, which requires a thorough understanding of scientific, medical, regulatory, industrial, and entrepreneurial issues; and on the other, the urgent need to train young researchers capable of working across these disciplines. In a landscape where therapeutic innovation is often slowed by institutional silos, insufficient dialogue between academia and industry, and overly specialized training pathways, this integrative and entrepreneurship-oriented approach is essential.
The objective is to prepare students to design and lead cross-disciplinary research projects by confronting them with real-world public health challenges. The methodology is built around the DDD Challenge, a full-scale exercise in which students identify an unmet medical need, design an interdisciplinary project ranging from proof-of-concept to potential technology transfer and entrepreneurial valorization, and defend their proposal before a mixed jury of academic and industrial experts. This immersion compels them to acquire not only scientific expertise but also skills in project management, communication, entrepreneurship, and valorization strategies.
The expected impact is already visible on several levels. Scientifically, the first funded projects have generated significant results, with some expected to be published before the completion of current PhD theses. From an educational perspective, students demonstrate exceptional maturity for their stage of training, both in their understanding of medical challenges and in their ability to organize, present, and defend their projects. In the long term, this initiative supports the emergence of a new generation of researchers and innovators capable of bridging academic research, clinical practice, the pharmaceutical industry, and entrepreneurship. We are confident that concrete applications arising from their discoveries will emerge in the coming years, directly contributing to improved medical practices and the development of novel therapeutic solutions

Laurence
SABATIER
Institution
Institut du médicament de Strasbourg
Country
France
Nationality
French
Related articles
Chronic & Non-communicable Diseases
Medical Treatment & Drug Development
AXA Project
France
Pain Pediatric & Elderly AXA Research Lab (PEARL)
Cutaneous neuropathic pain is a highly debilitating chronic condition, characterized by persistent sensations of burning, tingling, or hypersensitivity. It disproportionately... Read more
Celine
GRECO
Hôpital Necker-Enfants Malades
Medical Treatment & Drug Development
Mécénat des Mutuelle
France
New Molecule to Combat Antibiotic-Resistant Childhood Sepsis
The global spread of antibiotic resistance requires the identification of new bacterial drug targets, the design and synthesis of innovative... Read more

Nalini
RAMA RAO
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Medical Treatment & Drug Development
Post-Doctoral Fellowship
Germany
Fighting bacterial infection by targeting the ability of pathogens to hijack the body's defense system
Towards developing a new generation of antibiotics that target bacterial ubiquitin ligases used to hijack the host cells Dr. Timurs... Read more

Timurs
MACULINS